Weekly Q&A with Lauren Metliss June 2013
What is IVF?
Q: We’re having trouble conceiving but I’m hesitant in seeing a fertility specialist as I don’t think we are ready for IVF. To be honest, I don’t even really know what IVF is?
A: I think first up, its important to know that a visit to a fertility specialist doesn't always mean you will embark on an IVF cycle.
Fertility clinics offer cycle monitoring, ovulation induction (where ovulation is stimulated by clomid for example), intrauterine inseminations (where sperm is washed and inseminated into the uterus) and of course, IVF. Your specialist will order a range of tests for both you and your partner. These results can help to identify a reason for infertility and guide them in deciding the right treatment cycle for you.
IVF, or in vitro fertilisation, is the process where an egg from the female partner is placed together in a culture dish with many thousands of sperm prepared from a semen sample provided by the male partner. Over the next few hours, fertilisation takes place and a number of embryos are formed.
The fertilised embryos are developed in the laboratory over a period of two to five days, and then transferred to the woman’s uterus in a simple procedure called an embryo transfer.
Embryos are usually grown in the laboratory until Day 5, known as the Blastocyst stage, because there is strong evidence that these embryos are more likely to implant into the uterus during a fresh transfer. If more than two embryos develop, we can freeze those that are surplus for use in subsequent cycles.
This science has come a long way since the first IVF baby, Louise Brown, was born in 1978. We now can also add various techniques to the IVF process to help improve success rates:
- Intracytoplasmic sperm injection (ICSI) where a single sperm is injected into each egg by an embryologist.
- Polscope which uses polarised light to study the genetic material in the egg.
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- Assisted Hatching which involves using a laser to gently thin the outer shell of the egg.
- Digital high magnification of sperm whereby sperm images are magnified to over 7300x in order to select the best sperm for ICSI.
- PGD – Pre Genetic Diagnosis can identify the embryos that are chromosomally normal. The most common reason why IVF is unsuccessful is if too many or too few chromosomes are present (aneuploidy) in the transferred embryo.
- Surgical sperm collection is available if there are no sperm in the ejaculate.
Assisted Reproductive Treatment is a fascinating field helping many, many couples achieve their dream of becoming a family.
With one in six couples affected by infertility, please know you are not alone in your struggles. For further information you can browse IVF Australia’s website, or make an appointment with a fertility specialist in your area.
As always, we recommend if you are under 35 and have been trying for more than 12 months, or over 35 and trying for more than 6 months, please go and seek a specialist opinion.